Aromatase Inhibitors for Breast Cancer

However, Arimistane would make you look “drier” whereas a SERM only blocks estrogen in the breast tissue. It is thus important to choose the correct one for your situation. That said, many will use Arimistane as cycle support at 100 – 200mg per day, depending on a myriad of factors.

Exemestane

The current generation of nonsteroidal inhibitors includes anastrozole (Arimidex), letrozole (Femara), and vorozole https://intersel.com/steroids-understanding-their-use-risks-and-18/ (Rivizor), all of which are administered orally as a once-daily dose. The development of vorozole has been terminated, so it will not be discussed below. The only registered steroidal inhibitor of the current generation is exemestane (Aromasin). It is given as an injection into the abdomen (belly) once a month for 2–5 years to bring on temporary menopause. The drug may also help protect the ovaries during chemotherapy, so it is often given to women who want to preserve their fertility.

How Do I Take Hi-Tech Arimistane?

As such, it should come as little surprise that a widely diverse array of interventions has been tested. Aromatase inhibitors are another hormone treatment for breast cancer. Women who are post-menopausal, either naturally or as a result of treatment such as chemotherapy or surgical removal of the ovaries, may be prescribed aromatase inhibitors.

• Arimistane can be used up to 100mg per day, however, use too much and you severely limit the amount of muscle mass you end up building.
• The enzyme, localized in the endoplasmic reticulum of the estrogen-producing cell, is encoded by the CYP19A1 gene.
• Anastrozole, exemestane and letrozole are equally effective and have similar side effects 100, .
• This is particularly important in hormone-positive breast and ovarian cancers, which rely on estrogen for growth.

For more information, check out my completeNolvadex PCT guide. If you’re interested in running a post-cycle therapy (PCT) cycle using Clomid, look at my in-depth Clomid PCT guide. Keep in mind that Nolvadex is not useful for mitigating other types of estrogenic side effects besides gynecomastia.

What are the serious side effects of exemestane?

Food & Drug Administration approved and have been shown to be more effective than the antiestrogen drug tamoxifen in the postmenopausal population. There are three medications that are second-generation AIs, including anastrozole (Arimidex), letrozole (Femara), and exemestane (Aromasin). Estrogens are known to be important in the growth of breast cancers in both pre- and postmenopausal women. Although estrogens are no longer made in the ovaries after menopause, the body continues to make estrogen from other sources that could stimulate tumor growth. The clinical outcomes continue to improve in breast cancer treatment.